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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B3
All Species:
33.64
Human Site:
Y989
Identified Species:
49.33
UniProt:
Q15393
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15393
NP_036558.3
1217
135577
Y989
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Chimpanzee
Pan troglodytes
XP_511081
1283
142840
Y1055
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Rhesus Macaque
Macaca mulatta
XP_001107025
1199
133593
Y971
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Dog
Lupus familis
XP_536791
1217
135545
Y989
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q921M3
1217
135532
Y989
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Rat
Rattus norvegicus
XP_001077410
1216
135436
Y988
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506454
1217
135474
Y989
E
N
K
H
I
A
N
Y
I
S
G
I
Q
T
I
Chicken
Gallus gallus
XP_001232348
1218
135585
Y990
E
N
K
H
I
A
N
Y
I
C
G
I
Q
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVE8
1217
135603
L989
E
N
K
H
V
P
N
L
V
T
G
I
H
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728546
1227
136598
Q999
E
N
K
H
I
P
Y
Q
I
V
N
I
Q
A
M
Honey Bee
Apis mellifera
XP_623333
1217
135272
A989
E
N
K
H
I
P
N
A
V
V
S
I
N
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188711
1141
126889
F913
E
N
K
H
I
P
N
F
I
T
N
I
L
T
T
Poplar Tree
Populus trichocarpa
XP_002312063
1213
134429
S986
E
N
K
L
F
P
N
S
I
V
S
I
H
T
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49552
1088
121161
I868
E
C
G
H
H
G
H
I
L
A
L
Y
V
Q
T
Baker's Yeast
Sacchar. cerevisiae
Q04693
1361
153766
I1074
T
P
V
S
I
T
K
I
V
S
M
H
Q
W
N
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
L981
Q
A
D
V
T
P
T
L
I
V
S
L
Q
S
Q
Conservation
Percent
Protein Identity:
100
94.8
98.1
99.9
N.A.
99.9
99.5
N.A.
99.6
99
N.A.
93.4
N.A.
75.4
80.5
N.A.
76.1
Protein Similarity:
100
94.8
98.2
100
N.A.
100
99.5
N.A.
99.9
99.6
N.A.
97.9
N.A.
86.9
90.2
N.A.
85.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
60
N.A.
53.3
53.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
80
N.A.
60
60
N.A.
73.3
Percent
Protein Identity:
58.7
N.A.
N.A.
23.5
23
51
Protein Similarity:
76.1
N.A.
N.A.
42
41.5
69.5
P-Site Identity:
46.6
N.A.
N.A.
13.3
20
13.3
P-Site Similarity:
46.6
N.A.
N.A.
33.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
50
0
7
0
7
0
0
0
13
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
88
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
7
0
0
0
0
57
0
0
0
0
% G
% His:
0
0
0
82
7
0
7
0
0
0
0
7
13
0
0
% H
% Ile:
0
0
0
0
75
0
0
13
75
0
0
82
0
0
63
% I
% Lys:
0
0
82
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
13
7
0
7
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% M
% Asn:
0
82
0
0
0
0
75
0
0
0
13
0
7
0
7
% N
% Pro:
0
7
0
0
0
38
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
7
0
0
0
0
69
7
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
7
0
50
19
0
0
7
0
% S
% Thr:
7
0
0
0
7
7
7
0
0
13
0
0
0
69
13
% T
% Val:
0
0
7
7
7
0
0
0
19
25
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
7
50
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _